Unmatched Sequences in Public Databases - Exemplified by Tuberculin-Active Protein
نویسندگان
چکیده
منابع مشابه
Protein Databases
Proteins are sources of many peptides with diverse biological activity. Some of them are considered as valuable components of foods and drug targets with desired and designed biological activity. We are now entering an era rich in biological data in which the field of bioinformatics is poised to exploit this information in increasingly powerful ways. There are currently many databases all over ...
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Correct prediction of the structure of protein-coding genes of higher eukaryotes is still a difficult task; therefore, public databases are heavily contaminated with mispredicted sequences. The high rate of misprediction has serious consequences because it significantly affects the conclusions that may be drawn from genome-scale sequence analyses of eukaryotic genomes. Here we present the MisPr...
متن کاملDatabase tool MisPred: a resource for identification of erroneous protein sequences in public databases
Correct prediction of the structure of protein-coding genes of higher eukaryotes is still a difficult task; therefore, public databases are heavily contaminated with mispredicted sequences. The high rate of misprediction has serious consequences because it significantly affects the conclusions that may be drawn from genome-scale sequence analyses of eukaryotic genomes. Here we present the MisPr...
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MOTIVATION Sequence databases represent an enormous resource of phylogenetic information, but there is a lack of tools for accessing that information in order to assess the amount of evolutionary information in these databases that may be suitable for phylogenetic reconstruction and for identifying areas of the taxonomy that are under-represented for specific gene sequences. RESULTS We have d...
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This paper examines an emerging technology known as active databases. The focus is on issues which need to be considered in their development and the way they have been addressed in currently implemented systems. We examine what deenes active behavior, why it is useful, the semantics of its spec-iication and choices that have to be made when realising it in an actual system. We see that a multi...
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ژورنال
عنوان ژورنال: Scandinavian Journal of Immunology
سال: 2004
ISSN: 0300-9475,1365-3083
DOI: 10.1111/j.1365-3083.2004.1430.x